Abstract
Several novel copper(II) and zinc(II) complexes have been synthesized from Schiff base(s) obtained by the condensation of Knoevenagel condensate, 3-(3-phenyl-allylidene)-pentane-2,4-dione with p-substituted (X) aniline where X = –NO2 (L1), –H (L2), –OH (L3) and –OCH3 (L4)] and, copper(II) chloride/zinc(II) chloride. They have been characterized by analytical and spectral techniques. Electronic absorption and electrochemicalmeasurements prove that the complexes intercalate into DNA. Control DNA cleavage experiments using pUC19 supercoiled (SC) DNA and minor groove binder (distamycin) suggest the minor groove binding tendency for the synthesized complexes
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Innovative Research in Science, Engineering and Technology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
