Abstract
The sperm protective potential of Spondias mombin L in arsenic-treated rats was carried out. Thirty-five male albino rats (225 to 228 g) were used and grouped into 7 (A to G), each group containing 5 rats. Group A was treated with 0.1 ml dimethyl sulphoxide (DMSO), B (0.1 ml of distilled water), C (sodium arsenite (SA-2.5 mg/kg body weight), D (ethyl acetate fraction), E (ethyl acetate fraction for 7 days and sodium arsenite the 7th day), F (methanolic fraction for 7 days and sodium arsenite the 7th day) and G (methanolic fraction for 7 days). It was observed that groups G and E had the lowest percentage motility 25.00±15.00 and 38.00±13.90%, respectively which were significantly lower (P<0.05) than groups A and B (89.00±2.45 and 85.00±3.16%), respectively. Percentage motility of groups A to D was similar but higher (P<0.05) than groups E to G. The morphological characteristics ranged between 10.88 and 12.74% in all the groups. In this study, motility of the sperm cells in groups A to D and F were above 60%. This indicated that the sperm motility in these groups was not affected by the treatment. However, groups E and G showed a reduction in percentage motility and viability. The study concluded that S. mombin fractions did not affect sperm cells structurally but treatment with ethyl acetate and methanolic fraction caused significant reduction (P<0.05) in percentage motility and viability, thus may precipitate infertility. Key words: Spondias mombin, Wistar rats, spermatozoa characteristics, sperm morphology, sodium arsenite.
Highlights
Spondias mombin L. (Anarcardiaeae), synonym Spondias lutea, is commonly known as hog plum, yellow mombin or ubos
It was observed that groups G and E had the lowest percentage motility (25.00±15.00 and 38.00±13.90%), respectively and significantly lower (P
This indicated that the treatment did not affect the percentage motility negatively
Summary
Spondias mombin L. (Anarcardiaeae), synonym Spondias lutea, is commonly known as hog plum, yellow mombin or ubos. (Anarcardiaeae), synonym Spondias lutea, is commonly known as hog plum, yellow mombin or ubos. Called ‘atoaa’ in Ashanti, is a delicious erect tree which grows to 15 to 20 m tall with a trunk of 60 to 75 cm wide. It has a grayish bark, slightly buttressed, thick, coarse trunk (Burkill, 1985). It is traditionally known widely for the treatment of a variety of disease conditions. The bark is reported to reduce inflammation, relieve pain, reduce spasms, kill fungi
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
