English

Abstract

A procedure which calms the patient with good control on psychomotor response will help the surgeons to perform surgery with perfection. One such procedure is the chair side sedation. OBJECTIVE: Evaluation of sedation technique which involved titrating intravenous midazolam to an ideal sedation end point, followed by continuous infusion of propofol. This technique might be satisfactory alternative to general anaesthesia for implant surgery in anxious patients or when procedure exceeds 60 mins duration. MATERIAL AND METHOD: The study was conducted on 20 patients. Initially 2 mg bolus of midazolam was given then 1 mg dose of the same drug was given every 30 seconds until the patients was adequately sedated. 10 minutes after the induction of sedation with midazolam a continuous infusion of propofol was started at the rate of 0-200 mg per hour .The quality of sedation was assessed using Ellis and Sedation scores. RESULT: Total midazolam dosage for adequate initial sedation of patient was between 6 - 14 mg in 21 out of 23 treatment session. The initial propofol infusion rate was 200 mg per hour in most of the cases. CONCLUSION: The sedation technique describe takes advantage of the differing pharmacokinetics properties of midazolam and propofol initial sedation was achieved using midazolam which was maintained throughout the surgeries variable propofol infusion .