Abstract

The antioxidant activity of the essential oil was investigated using 2,2-diphenylpicrylhydrazyl (DPPH) radical scavenging assay and the β-carotene bleaching test. Butylated hydroxytoluene (BHT) was employed as a positive control. The essential oil showed antioxidant and DPPH radical scavenging activities, and it displayed the inhibition of lipid peroxidation. The antibacterial and antifungal activities of the essential oil of Canarium schweinfurthii from Centrafrican Republic were also evaluated against twelve strains of bacteria and three strains of fungi using agar diffusion and broth microdilution methods. The essential oil showed antimicrobial activity against almost the strains studied. The results suggest that C. schweinfurthii essential oil could be a natural antimicrobial and antioxidant agent.   Key words: Canarium schweinfurthii, Burceraceae, essential oil, antimicrobial, antioxidant.

Highlights

  • In the last years, scientists have focused on increasing human infections caused by pathogen bacteria, fungi and viruses

  • Canarium schweinfurthii Engl. (Burceracea) is a tree growing in the equatorial forest region from Cameroon, Centrafrican Republic, Gabon to Congo (Tchiégang, 2001; Tchouamo et al, 2000)

  • The antioxidant activity of C. schweinfurthii essential oil was investigated with two different methods: 2,2diphenylpicrylhydrazyl radical scavenging assay and carotene bleaching test

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Summary

Introduction

Scientists have focused on increasing human infections caused by pathogen bacteria, fungi and viruses. Synthetic chemicals are widely used against these microorganisms; they develop resistance to many antibiotics due to the indiscriminate use of commercial antibiotics (Service, 1995; Mukherjee et al, 2002). These antibiotics sometimes cause allergic reaction and immunity suppression. Previous studies on the isolation of lipids and fatty acids from the fruit and the human food, the chemical composition and the significant analgesic effect of the resin essential oil of C. schweinfurthii have been reported (Koudou et al, 2005; Agbo et al, 1992). The traditional use of the plant suggested an antioxidant activity

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