Abstract
Eremostachys laciniata (Lamiaceae) a rich source of structurally different flavonoids is ignored for its micronutrients level and many biological activities. In this study, the plant was investigated for different micronutrients including, phosphorus (P), nitrogen (N), boron (B), zinc (Zn) and manganese (Mn) and compared with adequate level of micronutrients for orchid crops. The crude methanol extract and different fractions of E. laciniata were also investigated for in vivo antinociceptive activity using Tail-flick model. Except for boron, all other micronutrients investigated were well in the limits recommended for orchid crops. Crude extract and different fraction thereof showed excellent increase in latency time along with certain central effect of causing sedation, ataxia and hind limb extension. This increase in latency time is not only due to analgesia but may be a combined effect of sedation, ataxia and analgesia. The plant may be a useful source in future for the isolation of natural product with analgesic property. Key words: Extract, fractions, nitrogen, orchid, analgesic
Highlights
Short CommunicationEvaluation of micronutrients level and antinociceptive property of Eremostachys laciniata (L) Bunge
Pain is an unpleasant subjective experience that is the net effect of a complex interaction of the ascending and descending nervous systems involving biochemical, physiological, psychological, and neocortical processes (Chisholm-Burns et al 2008)
The plant was investigated for different micronutrients including, phosphorus (P), nitrogen (N), boron (B), zinc (Zn) and manganese (Mn) and compared with adequate level of micronutrients for orchid crops
Summary
Evaluation of micronutrients level and antinociceptive property of Eremostachys laciniata (L) Bunge. Eremostachys laciniata (Lamiaceae) a rich source of structurally different flavonoids is ignored for its micronutrients level and many biological activities. The crude methanol extract and different fractions of E. laciniata were investigated for in vivo antinociceptive activity using Tailflick model. Crude extract and different fraction thereof showed excellent increase in latency time along with certain central effect of causing sedation, ataxia and hind limb extension. This increase in latency time is due to analgesia but may be a combined effect of sedation, ataxia and analgesia.
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