Abstract
This study was aimed to access the variations in serum lipid parameters based on the prandial state of adult patients. Through a cross-sectional descriptive and analytical study conducted in Parakou (Benin), from February 1 to May 1, 2020, 100 adult subjects (average age 31.21±12.36 years) were selected with systematic census. After ethical advice, a first sample was taken on empty-bellied adult subjects. Then, three additional samples were respectively taken two hours, four hours, and six hours after these subjects had eaten a meal of their choice. Serum lipid parameters were measured through enzymatic colorimetric methods. The average values of fasting lipid parameters in g/L were: Total cholesterol (1.48±0.35), HDL cholesterol (0.49±0.14), LDL cholesterol (0.84±0.36) and triglycerides (0.63±0.34). The comparison of the fasting and postprandial lipid parameters values is presented as follow: Triglyceridemia was significantly higher 2 h (P=0.000) and 4 h after meal (P=0.001). Only one type of food consumed was associated with mixed hyperlipidemia at six hours postprandial state (P=0.022). It may therefore be concluded that consumed foods do not cause most dyslipidemias 6 h in the postprandial state. During the screening for dyslipidemias in adults, the lipid profile can therefore be measured after six hours postprandial state. Key words: Lipid profile, fasting, prandial state, adults.
Highlights
Serum lipid profile is commonly determined for the cardiovascular risk prediction
Patients, including initial lipid profile testing in any patient, for cardiovascular risk assessment, patients admitted with acute coronary syndrome, in children, if preferred by the patient, in diabetic patients, in the elderly and patients on stable drug therapy; ii) fasting can sometimes be required if non-fasting triglycerides >5 mmol/L (440 mg/dL), known hypertriglyceridaemia followed in lipid clinic, recovering from hypertriglyceridaemic pancreatitis, starting
The results of this study showed that there was no significant difference between the values of total cholesterol, HDL cholesterol and LDL cholesterol (P>0.05) when compared fasting and postprandial lipid parameters
Summary
Serum lipid profile is commonly determined for the cardiovascular risk prediction. It is a routine medical examination that helps perform the screening of dyslipidemias (Nigam, 2011). Dyslipidemia is an important risk factor for coronary artery disease and stroke. The joint consensus statement from the European Atherosclerosis Society and European Federation of Clinical Chemistry and Laboratory Medicine recommend several conditions for lipid test: i) non-fasting in most patients, including initial lipid profile testing in any patient, for cardiovascular risk assessment, patients admitted with acute coronary syndrome, in children, if preferred by the patient, in diabetic patients (due to hypoglycaemic risk), in the elderly and patients on stable drug therapy; ii) fasting can sometimes be required if non-fasting triglycerides >5 mmol/L (440 mg/dL), known hypertriglyceridaemia followed in lipid clinic, recovering from hypertriglyceridaemic pancreatitis, starting.
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