Abstract

In Asian subcontinent, Caryota urens L. plant is well known. Its leaf has antioxidant and antimicrobial properties. The work aims to analyze the composition of the plant’s fruit extract and its aqueous and organic soluble fractions for its cytotoxic, thrombolytic, antioxidant, membrane stabilizing and antimicrobial properties. 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity assay, phosphomolybdenum total antioxidant assay and total phenolic content were used to evaluate the antioxidant activity. Brine shrimp lethality bioassay was used to determine the cytotoxic property. In thrombolytic activity assay, streptokinase was the standard. The samples were exposed to membrane stabilizing activity assay under heat and hypotonic solution-induced conditions. The samples’ antimicrobial potential was evaluated with Disc diffusion assay. The crude methanol extract showed   the highest free radical scavenging activity (IC50 = 62.74±0.16 μg/mL) that can correlate with its total phenolic content of 106.88±0.19 mg of GAE / g of sample. The crude methanol extract showed the highest cytotoxic potential (LC50 = 0.59±0.34 μg/mL). The carbon tetrachloride soluble materials revealed 20.48±0.44% of clot lysis in the assay for thrombolytic activity. The crude methanol extract prevented haemolysis of human erythrocytes in hypotonic solution-induced condition by 64.17±0.26%. Key words: Caryota urens L., free radical scavenging activity, brine shrimp lethality, thrombolysis, membrane stabilization. &nbsp

Highlights

  • Caryota urens L. (English name: Fishtail palm, Bengali name: Bonsupari) belongs to Arecaceae family

  • The crude methanol extract of C. urens fruits have a high content of phenolic principles (106.88±0.19 mg of GAE/g of sample)

  • The high phenolic content of C. urens extract might contribute to its antioxidant potentials

Read more

Summary

Introduction

Caryota urens L. (English name: Fishtail palm, Bengali name: Bonsupari) belongs to Arecaceae family. (English name: Fishtail palm, Bengali name: Bonsupari) belongs to Arecaceae family. The plant is a native of India, Myanmar and Sri lanka (Uddin et al, 2015). Root is used to treat tooth ailments. Flower is useful in gastric ulcer and migraine. Bark is used to treat rheumatic swellings and snake bite (Charles et al, 2011; Uddin et al, 2015). Recent scientific investigations report that C. urens sap is nutritionally rich

Methods
Results
Discussion
Conclusion

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.