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Abstract
The ethanol and water extracts of turmeric (Curcuma longa L.) displayed free radical scavenging activity. Chemical investigation of the ethanolic extract led to the isolation of a new acylated luteolin glucoside, luteolin-7-O-(6"-p-hydroxybenzoyl-b-D-glucopyranoside) (compound 1), together with the known flavonoids: luteolin 7-O-b-D-glucopyranoside (compound 2), apigenin-7-O-b-D-glucopyranoside (compound 3), luteolin (compound 4) and apigenin (compound 5) which were isolated for the first time from C. longa L. rhizomes, in addition to three diphenylheptanoids: curcumin (compound 6), demethoxycurcumin (compound 7) and bisdemethoxycurcumin (compound 8). The diphenylheptanoids have been previously reported for C. longa. Key words: Curcuma longa L., polyphenols constituents, luteolin-7-O-(6"-p-hydroxybenzoyl-b-glucopyranoside).
Highlights
The rhizomes of turmeric (C. longa L., Zingiberaceae) play an important role as a remedy for stomach and liver ailments
Curcuma longa L. extracts protected against cardiotoxicity induced by doxorubicin (El-Sayed et al, 2011)
This study reported the isolation and identification of a new compound from the ethanol extract of the dried powder of C. longa L. rhizomes: luteolin-7-O-(6"-phydroxybenzoyl- -D-glucopyranoside) together with seven known phenolic compounds 2 to 8
Summary
A new acylated luteolin glycoside from Curcuma Longa L. and free radical scavenging potential of its extracts. The ethanol and water extracts of turmeric (Curcuma longa L.) displayed free radical scavenging activity. Chemical investigation of the ethanolic extract led to the isolation of a new acylated luteolin glucoside, luteolin-7-O-(6"-p-hydroxybenzoyl- -D-glucopyranoside) (compound 1), together with the known flavonoids: luteolin 7-O- -D-glucopyranoside (compound 2), apigenin-7-O- -D-glucopyranoside (compound 3), luteolin (compound 4) and apigenin (compound 5) which were isolated for the first time from C. longa L. rhizomes, in addition to three diphenylheptanoids: curcumin (compound 6), demethoxycurcumin (compound 7) and bisdemethoxycurcumin (compound 8). The diphenylheptanoids have been previously reported for C. longa
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