English

Abstract

BACKGROUND: Cervical intra-epithelial neoplasia (CIN) and cervical cancer remain important health problems for women worldwide. It is largely a preventable disease that is characterized by a long lead time. The objective of this study was to determine the frequency of precancerous lesions of cervix by Pap smear screening. METHODS: A retrospective hospital based study was conducted at Department of Pathology, in a Tertiary Care Institute and associated hospital, Bhopal. Data was collected from the records of Pap's smear testing done on 388 patients in years 2011 & 2012. Analysis was done by entering data in SPSS software and Chi-square test was applied to find statistical significance. RESULTS: Most common lesions on Pap's smear was Low grade squamous intraepithelial lesion (LSIL) in 104 (26.8%) of cases and High grade squamous intraepithelial lesion (HSIL) in 15 (3.9%) of cases. 44 (11.3%) were senile Atopic Changes, parasitic Infection in 27 (7%) of cases and 2 (0.5%) were carcinoma cervix cases. All the cervical lesions were most common in age of 31-40 yrs. and were significantly associated with age. CONCLUSIONS: Pap's smear examination information should be spread in community apart from hospitals. Especially the young women should be motivated for regular Pap's smear. Pap's smear is the single most important screening method for early detection of precancerous & cancerous cervical lesions.