Abstract
AIMS: To study the prevalence of non-alcoholic fatty liver disease (NAFLD) in patients presenting for routine health check-up and To establish the relationship between NAFLD and various component of metabolic synbrome.PATIENTS AND METHODS: 500patients attending the medical OPD for health check-up had their blood pressure, height and weight, waist and hip circumference measurements, waist-hip ratio, blood sugars, lipid levels and ultrasound abdomen done after applying exclusion criterias.Those with normal ultrasound abdomen weretaken as control and those with NAFLD were taken as cases. The prevalence of NAFLD among these subjects was determined and the presence of risk factors for metabolic disease in each individual was analysed. A relationship between NAFLD and metabolic syndrome was then established.RESULTS: Of the 500people 198 (39.6%) had NAFLD.The prevalence is higher among females 127/282 (45%) than males 71/218 (32.6%).In the NAFLD group normal body mass index (BMI) was present in only 50/198 (25.3%) of the subjects while 89/198 (44.95%) were overweight and 59/198 (29.8%) were obese. Whereas in control group normal BMI was present in 199/302 (65.9%), overweight were 86/302 (28.5%) and only 17/198 (5.6%) were obese.Prevalence of metabolic syndrome was 137/198 (69.2%) among cases and 95/302 (31.5%) among controls.CONCLUSION: A diagnosis of fatty liver on ultrasound in an asymptomatic person should alert us of metabolic syndrome and its progression to cardiovascular disease. NAFLD may be considered as the hepatic component of metabolic syndrome.
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