Abstract
Malaria is one of the parasitic infections that cause enormous public health, economic, and emotional burden in many tropical and subtropical countries of the world. Resistance of the vector mosquitoes to the current insecticides as well as the emergence of multidrug resistance by malaria parasite to widely used antimalarial drugs has made malaria control and treatment much more difficult. New alternative antimalarial drugs and approaches for mosquito control are urgently required. Ethiopia, as most of the African continent countries, is rich in a wide range of tropical habitats, remarkable biodiversity, and the uses of traditional medicines for treatment of various illnesses. The article thus focuses on review of ethnopharmacological activities (medicinal properties), phytochemistry, and safety (toxicity) of some of the commonly used antimalarial herbal agents in Ethiopia and around which could have significant potential for antimalarial drug discovery and development. Key words: Medicinal plants, malaria, efficacy and safety, Ethiopia.
Highlights
In many developing nations of the world, large numbers of people still rely heavily on traditional healers and medicinal plants to meet their daily primary healthcare needs and overcome the problems of resistance and side effects of the currently available antimicrobial agents (Qais et al, 2011)
The estimates of malaria associated morbidity and mortality across the world are changing, as a recent report by the World Health Organization (WHO) indicated that promising malaria prevention and control measures, such as insecticide treated mosquito nets and indoor spraying with residual insecticides, have led to a significant drop of the mortality rate by 25% since 2000
In the sub acute toxicity test, both methanol and aqueous extracts of C. macrostachyus showed no significant difference in all the hematological parameters (body weight, packed cell volume (PCV) %, white blood cell (WBC) count, and hemoglobin) on day 4 after dosing as compared to that of day 0
Summary
A review of ethnopharmacology of the commonly used antimalarial herbal agents for traditional medicine practice in Ethiopia. Malaria is one of the parasitic infections that cause enormous public health, economic, and emotional burden in many tropical and subtropical countries of the world. Resistance of the vector mosquitoes to the current insecticides as well as the emergence of multidrug resistance by malaria parasite to widely used antimalarial drugs has made malaria control and treatment much more difficult. As most of the African continent countries, is rich in a wide range of tropical habitats, remarkable biodiversity, and the uses of traditional medicines for treatment of various illnesses. The article focuses on review of ethnopharmacological activities (medicinal properties), phytochemistry, and safety (toxicity) of some of the commonly used antimalarial herbal agents in Ethiopia and around which could have significant potential for antimalarial drug discovery and development
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
