Abstract
INTRODUCTION: Prevalence of sexual and reproductive function side effects of atypical antipsychotics is 18 to 96%contributingto non-compliance in 50% of treated patients.1 The abnormal ejaculation of semen is a typical and infrequent side effect of some α1-adrenoceptor antagonists. Iloperidone, a new dopamine type 2/serotonin type 2A antagonist provides better efficacy with less extra-pyramidal symptoms than D2 receptor antagonist antipsychotics. Iloperidone additionally has high affinity for alpha1 receptors and moderate affinity for alpha-2C receptors.2,3 Despite this knowledge, there is limited data regarding retrograde ejaculation caused due to use of Iloperidone. This article features three clinical cases of schizophrenia experiencing retrograde ejaculation after therapy with Iloperidone, treated successfully with Imipramine.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of Evolution of Medical and Dental Sciences
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
