Abstract

In the present study, polysaccharides have been isolated and evaluated as biological response modifiers in chickens. Aloe (A.) vera polysaccharides were administered in chickens for three consecutive days and used for immunological evaluation. Results showed significantly higher (p<0.05) lymphoproliferative response to PHA-P and Con-A in chickens of polysaccharides administered groups as compared to control. Carbon particle clearance assay showed significantly higher clearance index (K) in control group, indicating presence of more carbon particles in blood. Phagocytic index (α) showed significantly higher response in all three polysaccharides administered groups. Significantly higher humoral immune responses [total immunoglobulins (Igs), IgG and IgM titers] were also detected in treatment groups. Biomolecule administered chickens showed better feed conversion ratios and significantly higher (p<0.05) weekly weight gains. From the current study, it was concluded that A. vera derived polysaccharides have potential to be used as immunotherapeutic agent(s) in chickens. © 2016 Friends Science Publishers

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