Abstract
Engineered Vascularized Flaps In article number 2008687, Shulamit Levenberg and co-workers fabricate composite neo-tissue flaps by combining polymeric matrices and decellularized bone. These are perfused in vivo using hosts via a potent neo-vascular network. In vivo imaging is utilized to show how composite flaps support long-term bone repair and vascularization. This methodology may one day replace autologous tissue harvest from patients in need of tissue replacements.
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