Abstract
Engineered Spider Silk Protein In article number 2200986, Anna Rising and co-workers present the impressive strength of spider silk fibers conferred by poly-alanines in stacked β-sheets (steric zippers in pink). By protein engineering and expression in prokaryotic hosts, they have done what spiders cannot do: increase the hydrophobicity and intermolecular interactions of the steric zippers (turquoise) thereby generating stronger artificial spider silk.
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