Abstract
Human engineered heart tissues (EHTs) generated from induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are commonly retained optimal for the description of contraction parameters, but most of the EHTs’ mechanical measurements (i) are obtained from the optical detection of pillars’ displacement rather than being controlled force-length recordings (ii) are collected during spontaneous beating and (iii) have never been directly compared to myocardial twitches from cardiac patients samples.
Published Version
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