Abstract

The Galaxy platform is an open-source, Web-based platform for analyzing large biomedical datasets. Galaxy’s key motivations are: 1. Accessibility for everyone: scientists can use Galaxy’s Web-based interface to run complex analyses on large datasets using computing clusters or cloud computing with no programming; programmers can use Galaxy through its API, which provides programmatic access to all Galaxy functionality. 2. Reproducibility for all analyses: all analysis details, including input datasets, tool versions, and parameter settings, are saved so that an analysis can be precisely repeated by anyone with access to the analysis. 3. Web-based collaborative science: analyses can be shared with collaborators through a Web link, published to the entire Web, and included in Galaxy Pages, which are online, interactive research supplements. Engaging Biologists with Big Data Using Interactive Genome Annotation Jeremy Goecks1, Wilson Leung2, and Sarah C.R. Elgin2 1George Washington University and 2Washington University in St. Louis

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