Abstract
The liver, in addition to being a primary site for the metabolism of fat and carbohydrates, is central to the regulation of protein and energy metabolism. Excessive alcohol consumption is associated, through diverse biochemical and behavioral changes, with profound changes in fat, carbohydrate, and protein metabolism. It, therefore, is not surprising that alcoholic liver disease (ALD) frequently is associated with altered energy and protein metabolism. An appreciation of the physiologic role of the liver in energy and protein metabolism in health is a prerequisite to understanding the changes that occur in the setting of ALD.
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