Endovaskuläre Therapieoptionen der aneurysmatischen Subarachnoidalblutung

Abstract

Aneurysmal subarachnoid hemorrhaging (ASH) is a severe condition with an acute symptomatic, often with a difficult course and accompanied by many complications. Aneurysms can be detected using computed tomography (CT), magnetic resonance angiography (MRA) and digital subtraction angiography (DSA). Possible therapy options for ASH are surgical clipping and endovascular treatment using platinum coils. The surgical approach is an effective and safe method for avoiding recurrent bleeding.So-called Guglielmi detachable coils, with which aneurysms can be successfully embolized, have been available since 1991. Initially only a few different sizes of platinum coils were available but now complex forms of platinum coils with different lengths and rigidness are available so that many forms of aneurysm can be treated. Broad-based aneurysms, which could previously only be treated by surgery, can now be treated by the so-called balloon remodeling technique or stent-assisted coiling, whereby a balloon or stent is placed in the parent vessel to act as a scaffold for the coil. The results of the ISAT study demonstrated that a better outcome for patients could be achieved by endovascular treatment of aneurysms than by neurosurgical clipping of ruptured aneurysms. For this reason the first option should be endovascular treatment when possible. Asymptomatic aneurysms are being observed increasingly more often and primary treatment should be endovascular when possible. The somewhat higher re-bleeding rate for endovascular treatment could not diminish the better results of the ISAT study even during the 5-year follow-up.