Endovascular Treatment of Intracranial Anterior Circulation Aneurysms with Flow Diverters: A Single Centre Experience with mid and long-term results.

Abstract

We report our experience with flow diverter devices in the treatment of intracranial aneurysms arising from anterior circulation with mid and long-term follow-up. 78 aneurysms in 61 patients (range 25-81 years, 13 male, 48 female) were treated with flow diverter devices. 40 (51,3%) aneurysms were treated with pipeline embolization device (PED), 24 (30,8%) aneurysms were treated with SILK stent, 12(15,4%) aneurysms were treated with flow redirection endoluminal device (FRED) and two aneurysms were treated with P64 Flow Modulation Device (P64). Angiographic follow-up data at six month and one yea were recorded and the occlusion degrees of aneurysms were evaluated according to the scale which was formed by Kamran et al. At six month follow-up, complete occlusion (grade 4) rate was 60,8% and at one year increased to 74,3%. Statistical analysis revealed significant difference (p=0,002) between six month and one year follow-up results but there was no significant association (p=0,531, p=1,000) between aneurysm occlusion rate and aneurysm diameter. Two patient (3,2%) died due to hemorrhagic complication. Endovascular treatment of intracranial anterior circulation aneurysms with flow diverters is a safe and effective treatment option. A high rate of stable occlusion is achieved at long term follow-up.