Abstract

BackgroundDelayed arterial hemorrhage after pancreaticoduodenectomy is a life-threatening complication. There are no reports about infected aneurysms of the superior mesenteric artery after pancreaticoduodenectomy without clinically relevant pancreatic fistula.Case presentationA 78-year-old woman with borderline resectable pancreatic ductal adenocarcinoma involving the superior mesenteric arterial nerve plexus underwent pancreaticoduodenectomy with en bloc resection of the superior mesenteric vein and the superior mesenteric arterial nerve plexus after neoadjuvant chemotherapy. On postoperative day 14, she had bacteremia and sudden fever with chills. During the postoperative course, macroscopic abscesses or distinct infectious signs, including pancreatic fistula or bile fistula, were not present, but pylephlebitis was observed. After the antimicrobial treatment course, the patient was discharged. After 17 days, she was hospitalized for melena. Contrast-enhanced computed tomography showed a ruptured aneurysm of the superior mesenteric artery into the small intestine without a major intraabdominal abscess. E. coli was isolated from blood cultures. The patient was diagnosed with a ruptured infected aneurysm of the superior mesenteric artery. She was treated successfully with a covered stent by the cardiology team. There was no recurrence of bleeding at the 4-month follow-up, and the stent was patent in all subsequent computed tomography scans.ConclusionsEndovascular repair using a covered stent was effective in palliating acute bleeding from an infected aneurysm of the superior mesenteric artery.

Highlights

  • ConclusionsEndovascular repair using a covered stent was effective in palliating acute bleeding from an infected aneurysm of the superior mesenteric artery

  • Delayed arterial hemorrhage after pancreaticoduodenectomy is a life-threatening complication

  • Endovascular repair using a covered stent was effective in palliating acute bleeding from an infected aneurysm of the superior mesenteric artery

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Summary

Conclusions

Endovascular repair using a covered stent was effective in palliating acute bleeding from an infectious aneurysm of the SMA. Long-term antibiotic administration and follow-up blood cultures are necessary in cases of pylephlebitis after PD. Abbreviations PD: Pancreaticodudenectomy; DPH: Delayed postoperative hemorrhage; POPF: Postoperative pancreatic fistula; SMA: Superior mesenteric artery; POD: Postoperative day; CECT: Contrast-enhanced computed tomography; ISGPS: The International Study Group of Pancreatic Surgery; IE: Infective endocarditis.

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