Abstract
Nitric oxide (NO) is an endogenous vasodilator, which was described initially as endothelium-derived relaxing factor (EDRF) by Dr. Robert F. Furchgott. In 1978, he performed an experiment in his laboratory in New York that would lead to his realization that the presence of the endothelium is essential for the vasodilatory effect of acethylcholine. Twenty years after this key experiment, the Nobel prize was awarded to Dr. Furchgott (among others) for the discovery of EDRF. In Endothelium, Nitric Oxide, and Atherosclerosis: From Basic Mechanism to Clinical Implications, which was divided into 4 sections, the first chapter of the first section starts with a review of the discovery, biological roles, and regulation of endothelial NO by Dr. Furchgott himself. This chapter might be a valuable historical reference for anyone interested in this field. Endothelium, Nitric Oxide, and Atherosclerosis: From Basic Mechanism to Clinical Implications is a multiauthored exploration of endothelial cell function, NO, and atherosclerosis, focusing on physiology, biology, histology, and …
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
