Abstract

Address: 1Institute of Pharmacology and Experimental Toxicology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia, 2Ortline, Institute for Orthodontics and General Dentistry, 1000 Ljubljana, Slovenia, 3Department of Orthodontics, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia, 4Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia and 5Department of Medical and Natural Sciences, College of Health Care, University of Primorska, 6000 Koper, Slovenia

Highlights

  • The involvement of the endothelin signaling system during orthodontic tooth movement has not been explained yet

  • The aim of this study was to determine the role of endothelins ET-1, ET-2 and ET-3 and both receptor subtypes ETA and ETB during all the three phases of orthodontic tooth movement in a rat model

  • Orthodontic tooth movement was induced by a closed coil spring (F = 25 cN), which was placed between the upper left first molar and the upper incisors

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Summary

Open Access

Špela Sprogar*1,2, Alja Meh, Tomaž Vaupotiè, Andrej Cör, Martina Drevenšek and Gorazd Drevenšek. Address: 1Institute of Pharmacology and Experimental Toxicology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia, 2Ortline, Institute for Orthodontics and General Dentistry, 1000 Ljubljana, Slovenia, 3Department of Orthodontics, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia, 4Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia and 5Department of Medical and Natural Sciences, College of Health Care, University of Primorska, 6000 Koper, Slovenia. Published: 12 November 2009 BMC Pharmacology 2009, 9(Suppl 2):A64 doi:10.1186/1471-2210-9-S2-A64. 15th Scientific Symposium of the Austrian Pharmacological Society (APHAR) Andrea Laslop and Thomas Griesbacher Meeting abstracts - A single PDF containing all abstracts in this Supplement is available here. http://www.biomedcentral.com/content/pdf/1471-2210-9-S2-info.pdf

Background
Methods
Results
Conclusion

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