Abstract
Endothelin-1-like immunoreactivity has been found in endocrine cells of the midgut of the desert locust Locusta migratoria. Several antisera have been directed against the whole molecule and its C-terminal sequence. Endothelin-1-immunoreactive cells are present in the main region of the midgut (ventriculus) and in the midgut caeca but not in the ampullae through which the malpighian tubules drain. Endothelin-1-like immunoreactivity colocalizes with FMRFa immunoreactivity in the cells of the main region of the midgut but not in those in the midgut caeca. Endothelin-1-immunoreactive cells are present not only in adults but also throughout the five instars of posthatching development.
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