Abstract
Valve replacement has become the main treatment of valvular heart disease, but biological valve has been suffered from the problem of progressive degeneration and calcification after implantation, which is the main factor restricting the efficacy of heart valve replacement. Endothelial progenitor cells as precursor cells of mature endothelial cells, involved in embryonic angiogenesis and postnatal vascular and endothelial neoplasms. The function of endothelial progenitor cells to promote endothelial regeneration provides a new direction to solve the problem. Whether it can promote the re-endothelialization of implanted biological valve, and grow and reshape in the body, has become the hotspot. Key words: Endothelial progenitor cells; Tissue-engineered heart valves; Re-endothelialization
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