Abstract
Endothelial dysfunction is a predisposing factor for atherosclerosis and other cardiovascular diseases; and at the same time, endothelial dysfunction is associated to obesity. The prevalence of endothelial dysfunction, atherosclerosis and obesity is quite high among Mexican children; on the other hand, gut microbiota has been associated to obesity in the same population. Atherosclerosis is associated to gut microbiota in humans, and this association raise the possibility that endothelial dysfunction is also related with the gut microbiota in obese population. This review addresses the current knowledge of association of endothelial dysfunction, with obesity and atherosclerosis; however, there are no reports of association of endothelial dysfunction with gut microbiota through the measurement of adhesion molecules like ICAM-1, VCAM-1, and selectins. You can submit your Manuscripts at: https://symbiosisonlinepublishing.com/submitManuscript.php
Highlights
Atherosclerosis is a hardening process of the arteries, in which plaque builds up inside the arteries
A recent study showed that dietary fiber-free diet and captivity increases the intestinal colonization of bacteria Bacteroides spp. and Prevotella spp. in Non Human Primates (NHPs), which reflects in parallel the converge of NHPs microbiota towards the modern human microbiota, and suggests the recent loss of core microbiota in humans [24]
We found that the relative abundance of the phylum Firmicutes was more than the Bacteroidetes in obese children with high-level triglycerides and cholesterol
Summary
Endothelial Dysfunction in Mexican Obese Children, is there A Role of the Gut Microbiota?. Received: : December 01, 2016; Accepted: December 24, 2016; Published: January 04 , 2017
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