Abstract
Introduction : The human endosymbiotic actinidic archaea catabolises cholesterol and uses it for its energy metabolism. The ring oxidation of cholesterol generates pyruvate which enters the GABA shunt pathway resulting in the formation of succinyl CoA and glycine used for porphyrin synthesis. The side chain oxidation of cholesterol results in steroid synthesis and the generation of the steroidal glycoside digoxin which serves as an endogenous regulator of the sodium potassium pump inhibiting it. The archaea are magnetotactic and contain the dipolar porphyrins and magnetite. Digoxin by inhibiting the sodium potassium ATPase generates a pumped phonon system involving dipolar porphyrins and magnetite. This generates a frohlich model of Bose-Einstein condensate at normal temperature resulting in quantal perception. The quantal perception can result in perceiving low level of EMF from the environment. This can generate conscious perception. The generation of porphyrins and digoxin in actinidic archaeal neurons was tested in disorders of consciousness schizophrenia and autism. Schizophrenia and autism are both disorders of consciousness. Materials and Methods: Freshly diagnosed schizophrenia and autism based on DSM IV criteria were chosen for the study. Serum cytochrome 450, digoxin synthesis and porphyrin synthesis were studied. There were 10 patients in each group and each patient had an age and sex matched healthy control selected randomly from the general population. The blood samples were drawn in the fasting state before treatment was initiated. Plasma from fasting heparinised blood was used and the experimental protocol was as follows (I) Plasma+phosphate buffered saline, (II) same as I+cholesterol substrate, (III) same as II+cerium 0.1 mg/ml, (IV) same as II+ciprofloxacine and doxycycline each in a concentration of 1 mg/ml. Cholesterol substrate was prepared as described by Richmond. Aliquots were withdrawn at zero time immediately after mixing and after incubation at 37 o C for 1 hour. The following estimations were carried out:- Cytochrome F420, digoxin and ALA.Cytochrome F420 was estimated flourimetrically (excitation wavelength 420 nm and emission wavelength 520 nm). Results: Plasma of control subjects showed increased levels of the above mentioned parameters with after incubation for 1 hour and addition of cholesterol substrate resulted in still further significant increase in these parameters. The plasma of patients showed similar results but the extent of increase was more. The addition of antibiotics to the control plasma caused a decrease in all the parameters while addition of cerium increased their levels. The addition of antibiotics to the patient’s plasma caused a decrease in all the parameters while addition of cerium increased their levels but the extent of change was more in patient’s sera as compared to controls. Conclusion : The actinidic archaeal induced quantal perceptive mirror neuron function is hyperactive in both disorders. This results in dysfunction of consciousness due to increase in actinidic archaeal density, digoxin synthesis and porphyrin synthesis. Perception occurs predominantly by quantal perceptive mechanism in schizophrenia and autism. Thus the observer and observed depends on actinidic archaeal induced quantal perceptive mirror neuron function. The world as such is an illusion created by the inter-relationship between the observed and observer mediated by quantal perceptive mirror neurons. The quantal perceptive image of the world and the observer can exist as multiple possibilities in multiple universes leading to the phenomena of eternal existence in multiverse universes.
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