Abstract
Endoscopic procedures generate bacteraemia to different degrees. Under certain conditions, most notably valvular heart disease, clinically significant infections may occur. A large body of literature has grown around recommendations for antibiotic prophylaxis to prevent procedure-related infections. Most of this literature is in the form of anecdotal reports. Few prospective randomized studies have been performed. In this paper, the literature on endoscopy-related infections is reviewed. Recommendations for antibiotics from different sources are compared and a rational approach to prophylactic antibiotic therapy is presented.
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