Abstract
We read with interest the study by Thomas et al. [1] that highlighted the role of endoscopic ultrasound (EUS)-guided mural trucut biopsies (TCB) in patients with esophagogastric wall thickening and negative endoscopy and mucosal biopsies. The patients with thickened esophageal wall on computed tomography (CT) and normal mucosa on endoscopy as well as negative endoscopic biopsy pose a difficult diagnostic challenge. These patients usually undergo repeated endoscopic biopsies or fine-needle aspiration (FNA) under endoscopic guidance, with poor diagnostic yield. EUS-guided FNA has improved immensely our diagnostic capability but the sensitivity of this technique is low for focal mural lesions [2] [3]. The study by Thomas et al. [1] has shown that EUS-TCB is a safe technique with a high sensitivity for evaluating patients with unexplained esophagogastric wall thickening, and thus will help in solving clinical dilemmas like the one we encountered in one of our patients.
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