Abstract
Although endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is useful in the differential diagnosis of solid pancreatic lesions, lymph nodes, and liver lesions, inadequate sampling may result in an incorrect pathological diagnosis. The accuracy of EUS for the evaluation of pancreatobiliary lesions may be increased by image enhancement technologies, including contrast-enhanced harmonic (CH)-EUS and EUS-elastography. These methods can provide information that complement EUS-FNA for the diagnosis and staging of pancreatobiliary cancer, and can help to identify the EUS-FNA target, reducing the requirement for repeat FNA.
Highlights
Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) has been generally used since1992 for the sampling of pancreatobiliary tissues [1]
This review provides an overview of the ability of EUS-FNA with image enhancement to diagnose pancreatic tumors, lymph nodes, and liver tumors
With EUS-guided fine-needle biopsy (EUS-FNB) for the analysis of solid pancreatic lesions [26,27,28,29] revealed that fewer needle passes were required for EUS-FNB, there was no significant difference in the diagnostic yield between
Summary
Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) has been generally used since. Sampling errors can still occur and in real clinical situations, the final diagnosis is often an image-based diagnosis rather than a pathological diagnosis In such cases, endosonographers may experience difficulties in identifying the appropriate target of EUS-FNA. The accuracy of EUS for the evaluation of pancreatic lesions, lymph nodes, and liver lesions can be increased by image enhancement technologies, including contrast-enhanced harmonic (CH)-EUS and EUS-elastography. At present, both of these methods play important roles in the clinical evaluation of pancreatic cancer [8,9,10,11,12].
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