Endoscopic transnasal surgery for malignant sinus tumors involving orbit: clinical analyses of 34 cases

Abstract

To investigate the effect of endoscopic transnasal surgery for malignant sinus tumors involving the orbit, and to analyse the factors affecting the prognosis. Thirty-four cases of malignant sinus tumors involving the orbit, who underwent surgical treatment in Chinese people's liberation army general hospital between January 2009 and April 2015, were reviewed retrospectively. The 5-year survival rate, the recurrence rate and the complications was analysed, the factors affecting prognosis were discussed. Among 34 patients, 2 patients were lost to follow-up. Follow-up time of 32 patients ranged 7 to 75 months. The 5-year overall survival(OS)in this group was 53%. Twelve cases recurred, the recurrence rate was 35%. Eye function improved in 26 cases, the improvement rate was 76.5%. Four cases developed diplopia and peri-orbital swelling after surgery, and simple peri-orbit swelling in 25 cases. The 5-year survive rate of stage 1, stage 2 and stage 3 were 80%, 36% and 25%, respectively, with significant difference(χ(2)=6.643, P=0.036). Endoscopic transnasal surgery for malignant sinus tumors is effective, minimally invasive and accurate. The prognosis is closely related to the clinical stages and the pathological type.