Abstract

Background and objectiveEndoscopic submucosal dissection (ESD) is a minimal invasive technology and could allow “en bloc” resection for superficial gastric tumors. The aim of this study is to evaluate the safety and feasibility of ESD for gastric ectopic pancreas (EP).MethodsA total of 93 patients diagnosed with ectopic pancreas who underwent ESD between January 2011 and June 2017 were enrolled. The demographic, clinical, and endoscopic data were collected and analyzed.ResultsThe average maximal diameter of lesions was 1.01 (range 0.4–3.0) cm with mean age of patients which was 39.75 (range 15–66) years. Overall, all of procedures en bloc was successful. The median operative time was 76.87 (range 30–160) min. A total of 12 patients experienced complications. In seven patients, bleeding occurred during the operation and was treated using hot biopsy forceps or metal clip. Five cases suffered from pneumoperitoneum which was managed well. The mean length of postoperative hospital stay was 5.7 (range 2–17) days. There was no relapse in any cases during the follow-up.ConclusionESD appears to be a safe and feasible approach for curative treatment in gastric ectopic pancreas. Larger studies are needed to identify the role and the outcomes of ESD in another center.

Highlights

  • Ectopic pancreas is a congenital abnormal disease, and the incidence of ectopic pancreas (EP) ranges from 0.5 to 13% in the general population [1,2,3]

  • Gastric ectopic pancreas is defined as the pancreatic tissue located in the stomach which does not continue to the pancreas and has independent innervation and vascular supply [5]

  • Upper abdomen pain or discomfort, acid reflux, nausea, and vomiting are the common symptoms of gastric ectopic pancreas while these symptoms are not specific

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Summary

Introduction

Ectopic pancreas is a congenital abnormal disease, and the incidence of EP ranges from 0.5 to 13% in the general population [1,2,3]. Ectopic pancreas could occur anywhere in the gastrointestinal tract, but the most common site is stomach [4]. Gastric ectopic pancreas is defined as the pancreatic tissue located in the stomach which does not continue to the pancreas and has independent innervation and vascular supply [5]. Upper abdomen pain or discomfort, acid reflux, nausea, and vomiting are the common symptoms of gastric ectopic pancreas while these symptoms are not specific. It is difficult to distinguish EP with gastric submucosal tumors from the clinical manifestation. ESD is a minimally invasive approach for the treatment of. Endoscopic submucosal dissection (ESD) is a minimal invasive technology and could allow “en bloc” resection for superficial gastric tumors. The aim of this study is to evaluate the safety and feasibility of ESD for gastric ectopic pancreas (EP)

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