Abstract
Self-assembling peptides (PuraStat; 3-D Matrix, Tokyo, Japan) are novel synthetic self-assembling peptides that are licensed for use as a hemostat [1]. The matrix forms an extracellular scaffold that is activated by the change in pH on contact with blood and generates a stable mechanical barrier over the bleeding site, thereby facilitating intrinsic in vivo hemostasis [2]. Self-assembling peptides are mainly used to induce hemostasis of oozing bleeding in endoscopic procedures [3]; their usefulness in colorectal diverticular bleeding has yet to be investigated. In this study, we report a case in which the combination of self-assembling peptide solution and endoscopic band ligation (EBL) were effective for endoscopic hemostasis of spurting bleeding from a colonic diverticulum ([Video 1]).
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