Endoscopic Endonasal Transsphenoidal Approach to Large and Giant Pituitary Adenomas: Institutional Experience and Predictors of Extent of Resection

Abstract

Objective: While the use of endoscopic approaches has become increasingly accepted in the resection of pituitary adenomas, limited evidence exists regarding the success of this technique for patients with large and giant pituitary adenomas. This study presents the outcomes of a large cohort of patients with large and giant pituitary adenomas who underwent endoscopic endonasal transsphenoidal surgery (EETS) at our institution. It focuses on identifying factors that can predict extent of resection, and hence aid in developing guidelines and indications for the use of EETS versus open craniotomy approaches to large and giant pituitary adenomas.