Abstract

This is a 37-year-old woman who presented with weight gain, a moon-shaped face, and muscle weakness for 4 months. Cushing’s disease was confirmed after a series of diagnostic tests. MRI demonstrated a pituitary macroadenoma with right cavernous sinus invasion and encasement of the right ICA. An endoscopic endonasal approach was performed, and gross-total resection could be achieved without injury of the cranial nerves. The Cushing’s syndrome improved gradually after the surgery. Histopathology revealed a corticotroph adenoma. In this surgical video, we demonstrate the strategies of tumor resection according to a surgical anatomy-based classification of the cavernous sinus from an endonasal perspective.The video can be found here: https://youtu.be/aNXFRdGfjpI.

Highlights

  • This is a 37-year-old woman who presented with weight gain, a moon-shaped face, and muscle weakness for 4 months

  • MRI demonstrated a pituitary macroadenoma with right cavernous sinus invasion and encasement of the right ICA

  • We demonstrate the strategies of tumor resection according to a surgical anatomy-based classification of the cavernous sinus from an endonasal perspective

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Summary

Introduction

This is a 37-year-old woman who presented with weight gain, a moon-shaped face, and muscle weakness for 4 months. MRI demonstrated a pituitary macroadenoma with right cavernous sinus invasion and encasement of the right ICA. An endoscopic endonasal approach was performed, and gross-total resection could be achieved without injury of the cranial nerves. We demonstrate the strategies of tumor resection according to a surgical anatomy-based classification of the cavernous sinus from an endonasal perspective. KEYWORDS endonasal endoscopic approach; transcavernous approach; pituitary adenoma; Cushing’s disease; surgical video

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