Abstract

ABSTRACT Background: Craniopharyngiomas are challenging tumors that most frequently occur in the sellar or suprasellar regions. The endoscopic endonasal transsphenoidal approach is a minimal-invasive technique for managing craniopharyngiomas. The aim of this study is evaluation of endoscopic endonasal trans-sphenoidal approach in management of craniopharyngioma as regard the indications, operative difficulties, post-operative complications and outcomes. Patients and Methods: An analytical prospective study conducted on 12 Craniopharyngioma patients treated via endoscopic endonasal, trans-sphenoid approach in Al Azhar university hospitals. Follow up of patients done clinically and radiologically over 6 months. Results: The study included 12 patients, 2 (16.7%) males and 10 (83.3%) females, with mean age of 40 years. Gross total resection was achieved in 9 patients (75%). The most common surgical complication in our series was DI (50%), CSF rhinorrhea (33.3%) and DCL and seizures (16.7%) respectively. None of our patients suffered from worsening of endocrinological or visual outcome postoperatively. Conclusion: To conclude, Endoscopic Endonasal Approach (EEA) “either total or subtotal resection” is an effective surgical treatment for removal of craniopharyngiomas in terms of surgical outcome and tumor control. Key words: Craniopharyngioma; Endoscopy; Skull base; Endonasal Approach; Transsphenoidal surgery.

Highlights

  • Benign tumors resulting from squamous epithelial remains of Rathke’s pouch are craniopharyngiomas.These represent about 2-5 % of all intracranial tumors and about 5.6–13% in children

  • All patients had a mean age of the mean disease duration was (4 ± 1.4) months

  • The 12 craniopharyngioma patients were classified according to efficacy outcome “complete visual

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Summary

Introduction

Benign tumors resulting from squamous epithelial remains of Rathke’s pouch are craniopharyngiomas. These represent about 2-5 % of all intracranial tumors and about 5.6–13% in children. Craniopharyngiomas are uncommon, with just 5 % of patients among birth and 5 years of age.. The endoscopic endonasal transsphenoidal approach is a minimal-invasive technique for managing craniopharyngiomas. Aim of the study: is to evaluate of endoscopic endonasal transsphenoidal approach in management of craniopharyngioma as regard the indications, operative difficulties, post-operative complications and outcomes. Patients and Methods: An analytical prospective study conducted on 12 Craniopharyngioma patients treated via endoscopic endonasal, transsphenoid approach in Al Azhar university hospitals. Results: The study included 12 patients, 2 (16.7%) males and 10 (83.3%) females, with mean age of 40 years. Conclusion: The combination of IPACK block with ACB has the potential of being an adequate technique for management of acute postoperative pain after TKA but this needs more researches of larger samples and use of other types of local anesthetics with different volumes and concentrations

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