Abstract

Upper gastrointestinal bleeding (UGB) is a common medical emergency problem with significant morbidity and mortality. The aim of this paper is to establish the incidence of upper gastrointestinal bleeding in relation to sex and age, determine the prevalence of bleeding lesions and perform analysis of bleeding peptic ulcer in relation to the location, age, gender, Forrest classification and the need for endoscopic hemostasis. Thе prospective study included 70 patients with UGB, 42 men and 28 women, mean age 68.64±13.66 years. The diagnosis of bleeding lesions was made exclusively by means of esophagogastroduodenoscopy. Forrest classification was used in the evaluation of the activity of bleeding ulcers of the stomach and duodenum. The largest number of bleeding patients was of male sex (60%). Bleeding most commonly occurred in patients older than 60 years (84.29%). Statistically, female patients were significantly older than patients of male gender (p=0.001). The most common cause of bleeding was peptic ulcer (65.71%). The average age of patients with gastric ulcer was 70.57±15.68 years, with a duodenal ulcer 63.78±16.70 years. In the duodenum, Forrest Ib, IIa and IIb ulcers were usually confirmed, whereas Forrest IIc ulcers were identified in the stomach. Endoscopic hemostasis was required in 55.56% of patients with duodenal and in 23.81% of patients with gastric ulcer. The incidence of UGB is higher in men and it increases with age. The most common cause of bleeding is ulcer disease. Patients with gastric ulcer are older than patients with duodenal ulcer, while both gastric and duodenal ulcers are found in the oldest patients. Duodenal ulcers cause serious bleeding and more often require endoscopic hemostasis. Acta Medica Medianae 2015;54(2):24-30.

Highlights

  • Bleeding from the gastrointestinal (GI) tract represents a serious clinical problem, which in most cases requires hospitalization

  • Due to the extremely large heterogeneity, for didactic reasons, bleeding from the gastrointestinal tract is divided into upper gastrointestinal bleeding (UGB) and lower gastrointestinal bleeding (LGB)

  • Upper gastrointestinal bleeding refers to hemorrhage with the source of bleeding located at a point from the mouth to the ligament of Treitz, that is, from the esophagus, stomach and duodenum

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Summary

Introduction

Bleeding from the gastrointestinal (GI) tract represents a serious clinical problem, which in most cases requires hospitalization. Acute gastrointestinal bleeding often presents with dramatic clinical picture and requires urgent diagnostic and therapeutic procedures. For this reason, it ranks among the high-priority prehospital and hospital treatments [1]. Upper gastrointestinal bleeding refers to hemorrhage with the source of bleeding located at a point from the mouth to the ligament of Treitz, that is, from the esophagus, stomach and duodenum. Bleeding below this anatomical demarcation point is lower gastrointestinal bleeding and includes bleeding from the small intestine and colon [1,2]. Bleeding lesions are usually located in the upper gastrointestinal tract (80%), followed by the colon (20%), whereas bleeding from the small intestine is significantly lower (up to 2%) [3]

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