Abstract
Background: Endoscopic cryotherapy using low pressure liquid nitrogen spray is a new ablation technique for eliminating malignant and premalignant conditions of the esophagus. Aim: To evaluate the safety and tolerability of endoscopic cryotherapy ablation for malignant and premalignant conditions in the esophagus. Methods: Data from all patients treated under IRB-approved research protocol at 4 sites was analyzed. Conditions treated included Barrett's esophagus without dysplasia (BE), Barrett's esophagus with high-grade dysplasia (HGD) or intramucosal cancer (IMCA), esophageal carcinoma (T1 or T2 N0 M0), and severe squamous dysplasia (SSD).
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