Endoscopic closure of gastric full-thickness defects by application of metallic clips combined with a new type of endoloop

Abstract

Objective To evaluate a new type of endoloop for closure of full-thickness gastric defects left by EFR. Methods A total of 32 patients who underwent EFR at our hospital between October 2014 and February 2015 with gastric fundus submucosal tumors were retrospectively analyzed. After the resection, LeCamp™ endoloops and Olympus endoloops were used respectively to close the gastric defect in the study group(n=14) and the control group(n=18). The closure success rates, closure time, complications and the healing rates were compared. Results All lesions were removed by using EFR technique. The closure success rates of the two groups were both 100%. The closure time were 13.86±4.62 minutes and 18.28±6.48 minutes in study group and control group respectively with significant difference (P 0.05). One patient in study group and 2 patients in control group received abdominal puncture for relieving the pneumoperitoneum during the operation (P>0.05). No complications such as subcutaneous emphysema, pneumothorax, pneumomediastinum, delayed bleeding, or abdominal infection were found after the operations in either group. The wounds healed in all patients in 2 months after the procedure. Conclusion The use of novel endoloop and metallic clips is a relatively safe, easy, and feasible method for repairing large gastric post-EFR defects, which is of good clinical application value. Key words: Metallic clip; Endoloop; Endoscopic full-thick resection; Submucosal tumor