Abstract
To rapidly assess intraluminal pH during gastrointestinal endoscopy, 115 unselected patients were consecutively examined using Congo-red indicator (CRI) and phenol-red indicator (PRI) applied to the mucosa under direct vision. CRI was useful in screening for achlorhydria. PRI combined with CRI can confirm alkaline reflux in postgastrectomy gastritis. These agents were useful in the differential diagnosis of upper gastrointestinal hemorrhage. Alkaline reflux in the esophagus can be demonstrated by PRI. Endoscopic chemodiagnosis correlates visual and chemical findings. It can provide information otherwise requiring separate, costly, and time-consuming procedures.
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