Abstract
SummaryEye salvaging treatment of large uveal melanomas by primary irradiation bear the risk of severe secondary complications due to tumour regression. The so called „toxic tumour syndrome’ comprises a multitude of such problems such as retinal detachment, ocular ischemia, melanomalytic reactions, secondary glaucoma either by neovascularization or by tumour debris deposition or both. Surgical resection of tumours addresses these issues. Surgical resection can be performed either as an endoresection or as by means of transscleral resection. Both surgical procedures are challenging and pose by themselves some risks, which need to be addressed appropriately.
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