Endophytic, Non-endophytic Fungal Alkaloids and its Applications

Abstract

Alkaloids are a secondary metabolite, which are extracted from a wide – array of organisms include Bacteria, Fungi, Plants and Animals. Here in present review mainly focused on the alkaloids derived from endophytic fungi and non – endophytic fungi. Fungi have provided a great source of spirit for novel drug compounds as fungi derived alkaloids have done major boon to human health and well - being. In the present review listed 35 different group of alkaloids from endophytes. In which 12 different alkaloids are kept under derivatives of Indole group, 4 different alkaloids are kept under Quinoline group, 4 different alkaloids kept under amines and amide group, from non-endophytic alkaloid 27 different group of alkaloids are reported. In which 9 different type of alkaloid are mentioned under indole group of alkaloids, 4 alkaloids are reported under diketopiperazine alkaloids, 4 different alkaloids are mentioned under ergot group of alkaloids, 3 alkaloids under prenylated indole alkaloids, 3 alkaloids are mentioned under pyridine classes. The main applications of these alkaloids are antimicrobial, Antibacterial, Antifungal, Antiviral Activity Antihelmenthic, Anticancerous, Nutrient Pedaling, Photo stimulation, Endophytes in Tissue Culture Antidiabetic Activity, and Immunosuppressive Activity; hence all the alkaloids should be used as medicines in Ayurvedam. The alkaloids derived from different fungi were reviewed and their uses in medical fields were also report.