Abstract

Abstract The indolyl diketopiperazines ( 1 – 6 ) were isolated from the endophytic fungus Aspergillus tamarii in Ficus carica L. and tested for anti-phytopathogenic activity in vitro for the first time. Their structures were identified as fumitremorgin B (1), verruculogen (2), fumitremorgin C (3), cyclotryprostatins B (4), tryprostatin A (5) and tryprostatin B (6) respectively, based on spectroscopic analysis and by comparison of their spectral data with those reported previously in the literature. The anti-phytopathogenic activity of the isolated metabolites suggests that A. tamari could protect the host by producing the bioactive metabolites.

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