Abstract
For many years endometrium-like tissue has been recognized as occurring in the ovary, on the surface of the uterus, in the rectovaginal septum, in the umbilicus and elsewhere in the pelvis. To Sampson, however, belongs the credit for elucidating the pathologic nature and life history of the condition. In typical instances this tissue is histologically and functionally identical with the endometrium; its reaction to menstruation is evidenced by swelling, pain and tenderness at the menstrual periods as the result of the escape of blood into the glandular spaces. The formation of decidua in these misplaced glands has been shown to occur during intra-uterine pregnancy, and atrophy of these formations commonly follows cessation of ovarian function. On these facts are based the interpretations of the symptomatology and the principles underlying treatment. SYMPTOMATOLOGY The literature is replete with contributions dealing with the etiology of endometriosis, but it is remarkedly poor in those
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