Abstract

Oxidative stress (OS) is involved in the pathophysiology of endometriosis. OS induces alterations in the cytoskeleton (microtubules and chromosomes) of the oocyte. Disruption of the cytoskeleton may result in failure of the second meiotic division and consequently fertilization and implantation processes. We sought to study the alterations in the cytoskeleton and chromosome alignment of metaphase II oocytes incubated in the peritoneal fluid of patients with endometriosis.

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