Abstract
There is no screening program for ovarian or endometrial cancer. One reason for that could be the relatively low incidence with subsequently low positive predictive values for tests with low specifity. One way to address the problem could be the utilization of risk factors to define sub-populations with a higher incidence. Recently, there were hints that endometriosis could be a risk factor for ovarian cancer.
Highlights
No screening programs are available for ovarian or endometrial cancer
Descriptive statistics A total of 1305 participants were included in the analyses, of whom 165 were patients with ovarian cancer, 131 were patients with endometrial cancer, and 1016 were control individuals
Complete information with all variables was available for 90 % of the participants
Summary
No screening programs are available for ovarian or endometrial cancer. One reason for this is the low incidence of the conditions, resulting in low positive predictive values for tests, which are not very specific. The aim of this study was to investigate the extent to which a medical history of endometriosis can serve as a risk factor for ovarian or endometrial cancer. In the United States, the incidence of ovarian cancer is estimated to be around 22,200 annually. With regard to ovarian cancer, effective risk-reducing strategies have been described. Oral contraceptive use, and tubal ligation are associated with a significant reduction in the lifetime risk of ovarian cancer
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