Endometrial Histology in Abnormal Uterine Bleeding with Risk Factors

Abstract

Objective: To determine the endometrial histology in abnormal
 uterine bleeding (AUB) patients with risk factors.
 
 Method: This study involved 30 patients with complaints of AUB,
 aged over 35 years with associated risk factors of parity, obesity and
 fasting blood glucose in the outpatient clinic at Prof. Dr. R. D. Kandou
 General Hospital Manado, from July 2013 until October 2013.
 Patients who agreed to be involved in this study, underwent dilatation
 and curettage (D&C) to assess the endometrial histology that was
 grouped as the hyperplasia and non-hyperplasia groups.
 
 Result: From the results of the study, 7 patients were in the 35-40
 years age group (23.3%) and in the 41-50 years age group were 23 patients
 (76.7%). Based on parity, 11 patients (36.7%) were nulliparous
 and 19 patients (63.3%) were multiparous. Based on the BMI, 16 patients
 (53.5%) were obese and 14 patients (46.7%) were non-obese.
 And based on the results of fasting blood sugar, similar results was
 obtained in normal and abnormal fasting blood glucose with the results
 of 15 patients in each groups (50%). And from all of patients
 who underwent D&C, endometrial hyperplasia was shown in 21 patients
 (70%) and non-hyperplasia endometrium in 9 patients (30%).
 From the results of Fischer exact test, a significantly high association
 was obtained between BMI and fasting blood glucose with the occurrence
 of endometrial hyperplasia.
 
 Conclusion: There is a significant relationship between BMI and high
 fasting blood glucose with endometrial hyperplasia.
 [Indones J Obstet Gynecol 2015; 3: 146-150]
 Keywords: age, AUB, BMI, endometrial hyperplasia, fasting blood
 sugar, parity