Abstract
Endometrial carcinoma is a very rare cause of cutaneous metastasis. The most frequent presentations of cutaneous metastasis are fast developing nodules or tumors, which are evidence of widespread dissemination in such patients. We report a case of scalp metastasis from an endometrial adenocarcinoma with a fatal prognosis.
Highlights
INTRODUCTIONEndometrial adenocarcinoma is one of the most common gynecological tumors in postmenopausal women. 1 The distant metastasis of this type of tumor predominantly involves lungs, liver, bones[1] and cutaneous metastasis is documented in 0.7 to 9% of all neoplasms. 2
Endometrial adenocarcinoma is one of the most common gynecological tumors in postmenopausal women. 1 The distant metastasis of this type of tumor predominantly involves lungs, liver, bones[1] and cutaneous metastasis is documented in 0.7 to 9% of all neoplasms. 2The primary tumors most often metastasize to the cutaneous tissue are breast, colon, melanoma, and ovary
Endometrial carcinoma is a very rare cause of cutaneous metastasis, which mainly occurs due to hematogenous dissemination. 3,2 Metastatic lesions to the scalp may present in different forms, they are often highly vascular and reflect disseminated disease.[4,2]
Summary
Endometrial adenocarcinoma is one of the most common gynecological tumors in postmenopausal women. 1 The distant metastasis of this type of tumor predominantly involves lungs, liver, bones[1] and cutaneous metastasis is documented in 0.7 to 9% of all neoplasms. 2. The cutaneous metastasis of endometrial carcinoma, including scalp metastasis, is associated with a poor prognosis and a life expectancy of approximately 3 to 6 months.[5]. A rare case of scalp metastasis from endometrial carcinoma is presented. In this article, these cases are briefly described (table 1), in relation to the age of the patients, tumor type and stage, time until the appearance of cutaneous metastasis and time until the patient’s death. (figure 1) A biopsy was performed, which revealed cutaneous metastasis of adenocarcinoma with immune phenotype compatible with the previously diagnosed primary gynecological tumor. FONTE: Obstetrics and Gynaecology Department, Centro Hospitalar Tondela-Viseu Fig 2.A.: Hematoxylin-eosin, 4x – Skin biopsy with non-dysplastic epidermis; the dermis is occupied by densely cellular neoplastic proliferation. Histopathological and immunohistochemical features of cutaneous metastasis of endometrial carcinoma. 2A
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