Abstract

A carcass of nearly 7 year old intact female New Zealand White rabbit was presented for postmortem examination. On necropsy, both uterine horns were gray to black, markedly thickened, multinodular and occupied almost 35 to 40% space of abdominal cavity. Neoplastic nodules were soft and gray to black. Multinodular/polypoid coalescing masses were noted in uterine lumen. Neoplasm was metastasised to lungs and wall of thoracic cavity. On microscopic examination, moderately cellular neoplasm composed of polygonal cells that arranged in tubules or acini and separated by variably dense fibrovascular stroma. Within the neoplasm there were focal extensive to multifocal large areas of necrosis, hemorrhages and infiltration of inflammatory cells. Microscopically, metastasized neoplasm in lungs and thoracic wall showed similar histopathology. On the basis of histopathology, this neoplasm was diagnosed as endometrial carcinoma.

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