Endometrial adenocarcinoma following the conservative treatment of an atypical polypoid adenomyoma

Abstract

We present a case of well differentiated endometrioid adenocarcinoma of the endometrium in a 29-year-old woman, developing 6 months after an atypical polypoid adenomyoma (APA) was diagnosed by curettage. Four cases of APA with coexistent endometrial adenocarcinoma were recently reported. To our knowledge, this is the first reported case of endometrioid adenocarcinoma following conservative treatment for an APA. Since APA may be associated with the development of adenocarcinoma, careful follow-up with hysteroscopy and endometrial sampling is recommended in a woman with APA who desires continued fertility.